Media coverage (Forbes)
22. April 2016
Media coverage in the journal Forbes on the paper by Okbay et al. in Nature Genetics.
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News
Media coverage (Wirtschaftswoche)
21. April 2016
Media coverage by Wirtschaftswoche on the paper by Okbay et al. in Nature Genetics.
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Press release (MPIB Berlin)
20. April 2016
Press release of the Max Planck Institute for Human Development (MPIB) on a series of articles by investigators of the Berlin Aging Study II (BASE-II) in the journal Gerontology. The LIGA team spearheaded the analyses of the study by Lill et al.
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Press release (DIW Berlin)
19. April 2016
Press release of the Deutsches Institut für Wirtschaftsforschung (DIW) on the paper by Okbay A et al. in Nature Genetics.
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Press release (Uni Lübeck)
19. April 2016
Press release of the University of Lübeck on the paper by Okbay A et al. in Nature Genetics.
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Three new genes identified for subjective well-being
18. April 2016
This study was coordinated by the Social Science Genetics Association Consortium (SSGAC) of which our group is a member via contributing data from the Berlin Aging Study II. In total, our study investigated the data of nearly 300,000 individuals searching for genetic determinants of subjective well-being, depressive symptoms, and neuroticism. Using a genome-wide association study (GWAS) approach, we identified 16 signals associated with one of more of the investigated phenotypes. Pinpointed loci tended to be involved in regulating gene expression in the central nervous system and adrenal or pancreas tissues. The study was published in the journal Nature Genetics.
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April 5th: CBBM lecture on amyloid pathology in Alzheimer’s by Prof. Visser (VU Amsterdam)
4. April 2016
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Novel guidelines for preclinical Alzheimer’s disease
22. March 2016
Our group has participated in a recent effort to formulate novel recommendations about the definitions, the limits, the natural history, the markers of progression, and the ethical consequence of detecting Alzheimer’s disease at its preclinical, asymptomatic stage. This work is the result of a workshop held by the International Working Group (IWG) and the American Alzheimer’s Association on “The Preclinical State of AD” on July 23, 2015; Washington DC, USA. The guidelines were recently published in the journal Alzheimer’s & Dementia.
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March 8th: Seminar on micro RNAs in Alzheimer’s by Sebastien Hebert (Canada)
3. February 2016
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GWAS in >100,000 people identifies four novel loci for body fat
3. February 2016
For this study we participated in a consortium GWAS (genome-wide association study) meta-analysis on >100,000 individuals searching for novel loci underlying body fat and adiposity. The LIGA team contributed genome-wide data from the Berlin Aging Study II. Overall, a total of 12 genome-wide significant loci were identified of which four were novel. Additional analyses revealed associations of the body fat loci to a range of cardiometabolic traits providing new insights into the connection between adiposity and cardiovascular risk. The study was published in the journal Nature Communications.
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New results from the Berlin Aging Study II (BASE-II)
1. February 2016
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