GWAS in >100,000 people identifies four novel loci for body fat

For this study we participated in a consortium GWAS (genome-wide association study) meta-analysis on >100,000 individuals searching for novel loci underlying body fat and adiposity. The LIGA team contributed genome-wide data from the Berlin Aging Study II. Overall, a total of 12 genome-wide significant loci were identified of which four were novel. Additional analyses revealed associations of the body fat loci to a range of cardiometabolic traits providing new insights into the connection between adiposity and cardiovascular risk. The study was published in the journal Nature Communications.