New results from the Berlin Aging Study II (BASE-II)


This week, a string of seven papers describing new results from the Berlin Aging Study II (BASE-II) were published in the journal Gerontology, which devoted a entire issue to the topic. BASE-II is a multidisciplinary and multi-institutional project aiming to identify and characterize factors associated with ‘healthy’ vs. ‘unhealthy’ ageing. The molecular genetics experiments in BASE-II are led by researchers from LIGA. In our latest analyses, we could confirm and extend previous knowledge implying that both body mass index (BMI) and bone mineral density (BMD) have a polygenic basis. The special issue also included an editorial by the BASE-II principal investigators summarizing these newest findings.