Three new genes identified for subjective well-being
18. April 2016
This study was coordinated by the Social Science Genetics Association Consortium (SSGAC) of which our group is a member via contributing data from the Berlin Aging Study II. In total, our study investigated the data of nearly 300,000 individuals searching for genetic determinants of subjective well-being, depressive symptoms, and neuroticism. Using a genome-wide association study (GWAS) approach, we identified 16 signals associated with one of more of the investigated phenotypes. Pinpointed loci tended to be involved in regulating gene expression in the central nervous system and adrenal or pancreas tissues. The study was published in the journal Nature Genetics.