First genome-wide GxE study in PD published

3. August 2016

The LIGA team was part of a collaborative effort where we performed the first ever genome-wide gene-environment interaction (GxE) analysis of pesticide exposure and risk of Parkinson’s disease (PD). The results of this effort suggest that the effect of pesticide exposure on PD risk may be modified by SNPs in the ERCC6L2 gene. This finding needs to be replicated in independent samples before it should be considered as established. The results were published in the journal Parkinsonism and Related Disorders.