11. May 2016
This study is the second effort coordinated by the Social Science Genetics Association Consortium (SSGAC) to which LIGA contributed data from the Berlin Aging Study II. This newest analysis employed a genome-wide association study (GWAS) approach in 300,000 persons searching for genetic determinants of educational achievement, the largest-ever genetics study in the social sciences. A total of 74 loci were revealed to show genome-wide significant association with years of schooling. The identified loci were enriched for genomic regions regulating gene expression in the fetal brain. The study was published in the journal Nature.
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8. May 2016
News story in Welt am Sonntag from May 8th 2016 on the status of longevity research, including an interview with LIGA head Lars Bertram and LIGA collaborator Denis Gerstorf.
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22. April 2016
Media coverage in the journal Forbes on the paper by Okbay et al. in Nature Genetics.
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21. April 2016
Media coverage by Wirtschaftswoche on the paper by Okbay et al. in Nature Genetics.
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20. April 2016
Press release of the Max Planck Institute for Human Development (MPIB) on a series of articles by investigators of the Berlin Aging Study II (BASE-II) in the journal Gerontology. The LIGA team spearheaded the analyses of the study by Lill et al.
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19. April 2016
Press release of the Deutsches Institut für Wirtschaftsforschung (DIW) on the paper by Okbay A et al. in Nature Genetics.
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19. April 2016
Press release of the University of Lübeck on the paper by Okbay A et al. in Nature Genetics.
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18. April 2016
This study was coordinated by the Social Science Genetics Association Consortium (SSGAC) of which our group is a member via contributing data from the Berlin Aging Study II. In total, our study investigated the data of nearly 300,000 individuals searching for genetic determinants of subjective well-being, depressive symptoms, and neuroticism. Using a genome-wide association study (GWAS) approach, we identified 16 signals associated with one of more of the investigated phenotypes. Pinpointed loci tended to be involved in regulating gene expression in the central nervous system and adrenal or pancreas tissues. The study was published in the journal Nature Genetics.
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22. March 2016
Our group has participated in a recent effort to formulate novel recommendations about the definitions, the limits, the natural history, the markers of progression, and the ethical consequence of detecting Alzheimer’s disease at its preclinical, asymptomatic stage. This work is the result of a workshop held by the International Working Group (IWG) and the American Alzheimer’s Association on “The Preclinical State of AD” on July 23, 2015; Washington DC, USA. The guidelines were recently published in the journal Alzheimer’s & Dementia.
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