Publications

Vetter, VM, Drewelies, J, Düzel, S, Homann, J, Meyer-Arndt, L, Braun, J et al.. Change in body weight of older adults before and during the COVID-19 pandemic: longitudinal results from the Berlin Aging Study II. J Nutr Health Aging. 2024;28 (4):100206. doi: 10.1016/j.jnha.2024.100206. PubMed PMID:38460212 .

Deecke, L, Homann, J, Goldeck, D, Ohlei, O, Dobricic, V, Drewelies, J et al.. No increase of CD8+ TEMRA cells in the blood of healthy adults at high genetic risk of Alzheimer's disease. Alzheimers Dement. 2024; :. doi: 10.1002/alz.13709. PubMed PMID:38273437 .

Ohlei, O, Sommerer, Y, Dobricic, V, Homann, J, Deecke, L, Schilling, M et al.. Genome-wide QTL mapping across three tissues highlights several Alzheimer's and Parkinson's disease loci potentially acting via DNA methylation. medRxiv. 2023; :. doi: 10.1101/2023.12.22.23300365. PubMed PMID:38196633 PubMed Central PMC10775408.

Deecke, L, Ohlei, O, Homann, J, Stagge, J, Dobricic, V, Steinhagen-Thiessen, E et al.. Variants in the TERT Gene Increase the Occurrence of Solar Lentigines by Modifying Telomerase Expression Exclusively in the Skin. J Invest Dermatol. 2023; :. doi: 10.1016/j.jid.2023.10.034. PubMed PMID:38029837 .

Fjell, AM, Sørensen, Ø, Wang, Y, Amlien, IK, Baaré, WFC, Bartrés-Faz, D et al.. No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy. Nat Hum Behav. 2023;7 (11):2008-2022. doi: 10.1038/s41562-023-01707-5. PubMed PMID:37798367 PubMed Central PMC10663160.

Neumann, A, Ohlei, O, Küçükali, F, Bos, IJ, Timsina, J, Vos, S et al.. Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning. Genome Med. 2023;15 (1):79. doi: 10.1186/s13073-023-01233-z. PubMed PMID:37794492 PubMed Central PMC10548686.

Sommerer, Y, Dobricic, V, Schilling, M, Ohlei, O, Sabet, SS, Wesse, T et al.. Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer's disease. Alzheimers Res Ther. 2023;15 (1):92. doi: 10.1186/s13195-023-01232-7. PubMed PMID:37149695 PubMed Central PMC10163801.

Baalmann, N, Spielmann, M, Gillessen-Kaesbach, G, Hanker, B, Schmidt, J, Lill, CM et al.. Phenotypic specificity in patients with neurodevelopmental delay does not correlate with diagnostic yield of trio-exome sequencing. Eur J Med Genet. 2023;66 (7):104774. doi: 10.1016/j.ejmg.2023.104774. PubMed PMID:37120078 .

Zhou, LT, Liu, D, Kang, HC, Lu, L, Huang, HZ, Ai, WQ et al.. Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer's disease. Sci Adv. 2023;9 (16):eabq7105. doi: 10.1126/sciadv.abq7105. PubMed PMID:37083538 PubMed Central PMC10121173.

Kresojević, N, Marković, V, Dobričić, V, Stanković, I, Stojković, T, Tomić, A et al.. Reply to: "Differences in Sex-Specific Frequency of Glucocerebrosidase Variant Carriers and Familial Parkinsonism". Mov Disord. 2023;38 (4):712-713. doi: 10.1002/mds.29351. PubMed PMID:37061878 .

Shi, L, Xu, J, Green, R, Wretlind, A, Homann, J, Buckley, NJ et al.. Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease. Alzheimers Dement. 2023;19 (8):3350-3364. doi: 10.1002/alz.12961. PubMed PMID:36790009 .

Vetter, VM, Spieker, J, Sommerer, Y, Buchmann, N, Kalies, CH, Regitz-Zagrosek, V et al.. DNA methylation age acceleration is associated with risk of diabetes complications. Commun Med (Lond). 2023;3 (1):21. doi: 10.1038/s43856-023-00250-8. PubMed PMID:36765171 PubMed Central PMC9918553.

Foddis, M, Blumenau, S, Holtgrewe, M, Paquette, K, Westra, K, Alonso, I et al.. TREX1 p.A129fs and p.Y305C variants in a large multi-ethnic cohort of CADASIL-like unrelated patients. Neurobiol Aging. 2023;123 :208-215. doi: 10.1016/j.neurobiolaging.2022.11.013. PubMed PMID:36586737 .

Lee, S, Hahn, G, Hecker, J, Lutz, SM, Mullin, K, Alzheimer’s Disease Neuroimaging Initiative (ADNI) et al.. A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets. Brief Bioinform. 2023;24 (1):. doi: 10.1093/bib/bbac611. PubMed PMID:36585781 PubMed Central PMC9851291.

Zhang, Y, Ghose, U, Buckley, NJ, Engelborghs, S, Sleegers, K, Frisoni, GB et al.. Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks. Front Aging Neurosci. 2022;14 :1040001. doi: 10.3389/fnagi.2022.1040001. PubMed PMID:36523958 PubMed Central PMC9746615.

Küçükali, F, Neumann, A, Van Dongen, J, De Pooter, T, Joris, G, De Rijk, P et al.. Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits. Alzheimers Dement. 2023;19 (6):2317-2331. doi: 10.1002/alz.12842. PubMed PMID:36464806 .

Algharably, EA, Villagomez Fuentes, LE, Toepfer, S, König, M, Regitz-Zagrosek, V, Bertram, L et al.. Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men. J Hum Hypertens. 2023;37 (8):709-717. doi: 10.1038/s41371-022-00781-y. PubMed PMID:36443444 PubMed Central PMC10403350.

Dobricic, V, Schilling, M, Farkas, I, Gveric, DO, Ohlei, O, Schulz, J et al.. Common signatures of differential microRNA expression in Parkinson's and Alzheimer's disease brains. Brain Commun. 2022;4 (6):fcac274. doi: 10.1093/braincomms/fcac274. PubMed PMID:36382223 PubMed Central PMC9645562.

Sommerer, Y, Dobricic, V, Schilling, M, Ohlei, O, Bartrés-Faz, D, Cattaneo, G et al.. Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans. Biomedicines. 2022;10 (11):. doi: 10.3390/biomedicines10112798. PubMed PMID:36359320 PubMed Central PMC9687249.

Sommerer, Y, Ohlei, O, Dobricic, V, Oakley, DH, Wesse, T, Sedghpour Sabet, S et al.. A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples. Clin Epigenetics. 2022;14 (1):139. doi: 10.1186/s13148-022-01357-w. PubMed PMID:36320053 PubMed Central PMC9628033.

Nyberg, L, Andersson, M, Lundquist, A, Baaré, WFC, Bartrés-Faz, D, Bertram, L et al.. Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates. Cereb Cortex. 2023;33 (9):5075-5081. doi: 10.1093/cercor/bhac400. PubMed PMID:36197324 PubMed Central PMC10151879.

Vetter, VM, Drewelies, J, Sommerer, Y, Kalies, CH, Regitz-Zagrosek, V, Bertram, L et al.. Epigenetic aging and perceived psychological stress in old age. Transl Psychiatry. 2022;12 (1):410. doi: 10.1038/s41398-022-02181-9. PubMed PMID:36163242 PubMed Central PMC9513097.

Drewelies, J, Hueluer, G, Duezel, S, Vetter, VM, Pawelec, G, Steinhagen-Thiessen, E et al.. Using blood test parameters to define biological age among older adults: association with morbidity and mortality independent of chronological age validated in two separate birth cohorts. Geroscience. 2022;44 (6):2685-2699. doi: 10.1007/s11357-022-00662-9. PubMed PMID:36151431 PubMed Central PMC9768057.

Jansen, IE, van der Lee, SJ, Gomez-Fonseca, D, de Rojas, I, Dalmasso, MC, Grenier-Boley, B et al.. Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers. Acta Neuropathol. 2022;144 (5):821-842. doi: 10.1007/s00401-022-02454-z. PubMed PMID:36066633 PubMed Central PMC9547780.

Dobricic, V, Schilling, M, Schulz, J, Zhu, LS, Zhou, CW, Fuß, J et al.. Differential microRNA expression analyses across two brain regions in Alzheimer's disease. Transl Psychiatry. 2022;12 (1):352. doi: 10.1038/s41398-022-02108-4. PubMed PMID:36038535 PubMed Central PMC9424308.

Morgan, SL, Naderi, P, Koler, K, Pita-Juarez, Y, Prokopenko, D, Vlachos, IS et al.. Most Pathways Can Be Related to the Pathogenesis of Alzheimer's Disease. Front Aging Neurosci. 2022;14 :846902. doi: 10.3389/fnagi.2022.846902. PubMed PMID:35813951 PubMed Central PMC9263183.

Delvenne, A, Gobom, J, Tijms, B, Bos, I, Reus, LM, Dobricic, V et al.. Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology. Alzheimers Dement. 2022; :. doi: 10.1002/alz.12713. PubMed PMID:35698882 .

Lill, CM, Bertram, L. Genome-wide analysis furthers decoding of Alzheimer disease genetics. Nat Rev Neurol. 2022;18 (7):387-388. doi: 10.1038/s41582-022-00678-x. PubMed PMID:35624172 .

Wesenhagen, KEJ, Gobom, J, Bos, I, Vos, SJB, Martinez-Lage, P, Popp, J et al.. Effects of age, amyloid, sex, and APOE ε4 on the CSF proteome in normal cognition. Alzheimers Dement (Amst). 2022;14 (1):e12286. doi: 10.1002/dad2.12286. PubMed PMID:35571963 PubMed Central PMC9074716.

Vetter, VM, Sommerer, Y, Kalies, CH, Spira, D, Bertram, L, Demuth, I et al.. Vitamin D supplementation is associated with slower epigenetic aging. Geroscience. 2022;44 (3):1847-1859. doi: 10.1007/s11357-022-00581-9. PubMed PMID:35562603 PubMed Central PMC9213628.

Visser, PJ, Reus, LM, Gobom, J, Jansen, I, Dicks, E, van der Lee, SJ et al.. Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. Mol Neurodegener. 2022;17 (1):37. doi: 10.1186/s13024-022-00540-0. PubMed PMID:35550177 PubMed Central PMC9102351.

Youn, C, Grotzinger, AD, Lill, CM, Bertram, L, Schmiedek, F, Lövdén, M et al.. Genetic associations with learning over 100 days of practice. NPJ Sci Learn. 2022;7 (1):7. doi: 10.1038/s41539-022-00121-2. PubMed PMID:35508486 PubMed Central PMC9068685.

Homann, J, Osburg, T, Ohlei, O, Dobricic, V, Deecke, L, Bos, I et al.. Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset. Front Aging Neurosci. 2022;14 :840651. doi: 10.3389/fnagi.2022.840651. PubMed PMID:35386118 PubMed Central PMC8979334.

Okbay, A, Wu, Y, Wang, N, Jayashankar, H, Bennett, M, Nehzati, SM et al.. Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals. Nat Genet. 2022;54 (4):437-449. doi: 10.1038/s41588-022-01016-z. PubMed PMID:35361970 PubMed Central PMC9005349.

Visser, PJ, Reus, LM, Gobom, J, Jansen, I, Dicks, E, van der Lee, SJ et al.. Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. Mol Neurodegener. 2022;17 (1):27. doi: 10.1186/s13024-022-00521-3. PubMed PMID:35346299 PubMed Central PMC8962234.

Prokopenko, D, Lee, S, Hecker, J, Mullin, K, Morgan, S, Katsumata, Y et al.. Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2. Mol Psychiatry. 2022;27 (4):1963-1969. doi: 10.1038/s41380-022-01475-0. PubMed PMID:35246634 PubMed Central PMC9126808.

Kusters, CDJ, Paul, KC, Duarte Folle, A, Keener, AM, Bronstein, JM, Bertram, L et al.. Erratum to "Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Approach". Mov Disord. 2022;37 (6):1282-1283. doi: 10.1002/mds.28974. PubMed PMID:35245402 PubMed Central PMC10566527.

Neumann, A, Küçükali, F, Bos, I, Vos, SJB, Engelborghs, S, De Pooter, T et al.. Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation. Mol Psychiatry. 2022;27 (4):1990-1999. doi: 10.1038/s41380-022-01437-6. PubMed PMID:35173266 PubMed Central PMC9126805.

Prokopenko, D, Morgan, SL, Lange, C, Hide, W, Bertram, L, Tanzi, RE et al.. Reply to Neupane et al.: Replication study of AD-associated rare variants. Alzheimers Dement. 2022;18 (4):863-864. doi: 10.1002/alz.12584. PubMed PMID:35142036 PubMed Central PMC9302627.

Vetter, VM, Kalies, CH, Sommerer, Y, Bertram, L, Demuth, I. Seven-CpG DNA Methylation Age Determined by Single Nucleotide Primer Extension and Illumina's Infinium MethylationEPIC Array Provide Highly Comparable Results. Front Genet. 2021;12 :759357. doi: 10.3389/fgene.2021.759357. PubMed PMID:35111197 PubMed Central PMC8802213.

Vetter, VM, Kalies, CH, Sommerer, Y, Spira, D, Drewelies, J, Regitz-Zagrosek, V et al.. Relationship Between 5 Epigenetic Clocks, Telomere Length, and Functional Capacity Assessed in Older Adults: Cross-Sectional and Longitudinal Analyses. J Gerontol A Biol Sci Med Sci. 2022;77 (9):1724-1733. doi: 10.1093/gerona/glab381. PubMed PMID:35032170 .

Kresojević, N, Dobričić, V, Lukić, MJ, Tomić, A, Petrović, I, Dragašević, N et al.. Genetic and phenotypic variability in adult patients with Niemann Pick type C from Serbia: single-center experience. J Neurol. 2022;269 (6):3167-3174. doi: 10.1007/s00415-021-10918-7. PubMed PMID:34993563 .

Wang, Y, Grydeland, H, Roe, JM, Pan, M, Magnussen, F, Amlien, IK et al.. Associations of circulating C-reactive proteins, APOE ε4, and brain markers for Alzheimer's disease in healthy samples across the lifespan. Brain Behav Immun. 2022;100 :243-253. doi: 10.1016/j.bbi.2021.12.008. PubMed PMID:34920091 .

Xu, J, Green, R, Kim, M, Lord, J, Ebshiana, A, Westwood, S et al.. Sex-Specific Metabolic Pathways Were Associated with Alzheimer's Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort. Biomedicines. 2021;9 (11):. doi: 10.3390/biomedicines9111610. PubMed PMID:34829839 PubMed Central PMC8615383.

Vidal-Pineiro, D, Wang, Y, Krogsrud, SK, Amlien, IK, Baaré, WFC, Bartres-Faz, D et al.. Individual variations in 'brain age' relate to early-life factors more than to longitudinal brain change. Elife. 2021;10 :. doi: 10.7554/eLife.69995. PubMed PMID:34756163 PubMed Central PMC8580481.

Karalija, N, Köhncke, Y, Düzel, S, Bertram, L, Papenberg, G, Demuth, I et al.. A common polymorphism in the dopamine transporter gene predicts working memory performance and in vivo dopamine integrity in aging. Neuroimage. 2021;245 :118707. doi: 10.1016/j.neuroimage.2021.118707. PubMed PMID:34742942 .

Villagomez Fuentes, LE, Algharably, EA, Toepfer, S, König, M, Demuth, I, Bertram, L et al.. Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults. J Hum Hypertens. 2022;36 (11):983-988. doi: 10.1038/s41371-021-00608-2. PubMed PMID:34593962 PubMed Central PMC9649423.

Wagner, M, Lorenz, G, Volk, AE, Brunet, T, Edbauer, D, Berutti, R et al.. Clinico-genetic findings in 509 frontotemporal dementia patients. Mol Psychiatry. 2021;26 (10):5824-5832. doi: 10.1038/s41380-021-01271-2. PubMed PMID:34561610 PubMed Central PMC8758482.

Tijms, BM, Gobom, J, Teunissen, C, Dobricic, V, Tsolaki, M, Verhey, F et al.. CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals. Proteomes. 2021;9 (3):. doi: 10.3390/proteomes9030036. PubMed PMID:34449748 PubMed Central PMC8396164.

Balck, A, Schaake, S, Kuhnke, NS, Domingo, A, Madoev, H, Margolesky, J et al.. Genotype-Phenotype Relations in Primary Familial Brain Calcification: Systematic MDSGene Review. Mov Disord. 2021;36 (11):2468-2480. doi: 10.1002/mds.28753. PubMed PMID:34432325 .

Kusters, CDJ, Paul, KC, Duarte Folle, A, Keener, AM, Bronstein, JM, Bertram, L et al.. Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Randomization Approach. Mov Disord. 2021;36 (10):2264-2272. doi: 10.1002/mds.28760. PubMed PMID:34426982 PubMed Central PMC8530889.

Wittke, C, Petkovic, S, Dobricic, V, Schaake, S, MDS‐endorsed PSP Study Group, Respondek, G et al.. Genotype-Phenotype Relations for the Atypical Parkinsonism Genes: MDSGene Systematic Review. Mov Disord. 2021;36 (7):1499-1510. doi: 10.1002/mds.28517. PubMed PMID:34396589 PubMed Central PMC9070562.

Shi, L, Buckley, NJ, Bos, I, Engelborghs, S, Sleegers, K, Frisoni, GB et al.. Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies. Front Aging Neurosci. 2021;13 :712545. doi: 10.3389/fnagi.2021.712545. PubMed PMID:34366831 PubMed Central PMC8335587.

Reyes, CJ, Laabs, BH, Schaake, S, Lüth, T, Ardicoglu, R, Rakovic, A et al.. Brain Regional Differences in Hexanucleotide Repeat Length in X-Linked Dystonia-Parkinsonism Using Nanopore Sequencing. Neurol Genet. 2021;7 (4):e608. doi: 10.1212/NXG.0000000000000608. PubMed PMID:34250228 PubMed Central PMC8265576.

Schilling, M, Lill, CM. MicroRNAs as Molecular Biomarkers for Parkinson's Disease Progression. Mov Disord. 2021;36 (8):1793. doi: 10.1002/mds.28700. PubMed PMID:34223665 .

Demuth, I, Banszerus, V, Drewelies, J, Düzel, S, Seeland, U, Spira, D et al.. Cohort profile: follow-up of a Berlin Aging Study II (BASE-II) subsample as part of the GendAge study. BMJ Open. 2021;11 (6):e045576. doi: 10.1136/bmjopen-2020-045576. PubMed PMID:34162642 PubMed Central PMC8230995.

Radojević, B, Dragašević-Mišković, NT, Marjanović, A, Branković, M, Dobričić, V, Milovanović, A et al.. Clinical and Genetic Analysis of Psychosis in Parkinson's Disease. J Parkinsons Dis. 2021;11 (4):1973-1980. doi: 10.3233/JPD-212716. PubMed PMID:34151861 .

Laabs, BH, Klein, C, Pozojevic, J, Domingo, A, Brüggemann, N, Grütz, K et al.. Identifying genetic modifiers of age-associated penetrance in X-linked dystonia-parkinsonism. Nat Commun. 2021;12 (1):3216. doi: 10.1038/s41467-021-23491-4. PubMed PMID:34050153 PubMed Central PMC8163740.

Hong, S, Dobricic, V, Ohlei, O, Bos, I, Vos, SJB, Prokopenko, D et al.. TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels. Alzheimers Dement. 2021;17 (10):1628-1640. doi: 10.1002/alz.12330. PubMed PMID:33991015 .

Grydeland, H, Sederevičius, D, Wang, Y, Bartrés-Faz, D, Bertram, L, Dobricic, V et al.. Self-reported sleep relates to microstructural hippocampal decline in ß-amyloid positive Adults beyond genetic risk. Sleep. 2021;44 (11):. doi: 10.1093/sleep/zsab110. PubMed PMID:33912975 PubMed Central PMC8598196.

Nyberg, L, Magnussen, F, Lundquist, A, Baaré, W, Bartrés-Faz, D, Bertram, L et al.. Educational attainment does not influence brain aging. Proc Natl Acad Sci U S A. 2021;118 (18):. doi: 10.1073/pnas.2101644118. PubMed PMID:33903255 PubMed Central PMC8106299.

Prokopenko, D, Morgan, SL, Mullin, K, Hofmann, O, Chapman, B, Kirchner, R et al.. Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. Alzheimers Dement. 2021;17 (9):1509-1527. doi: 10.1002/alz.12319. PubMed PMID:33797837 PubMed Central PMC8519060.

Shi, L, Winchester, LM, Westwood, S, Baird, AL, Anand, SN, Buckley, NJ et al.. Replication study of plasma proteins relating to Alzheimer's pathology. Alzheimers Dement. 2021;17 (9):1452-1464. doi: 10.1002/alz.12322. PubMed PMID:33792144 .

Lill, CM. Transcriptome-wide Association Study in Frontotemporal Dementia Identifies New Disease Loci by In Silico Analysis. Biol Psychiatry. 2021;89 (8):e37-e39. doi: 10.1016/j.biopsych.2021.02.010. PubMed PMID:33766241 .

Messerschmidt, C, Foddis, M, Blumenau, S, Müller, S, Bentele, K, Holtgrewe, M et al.. PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice. Sci Rep. 2021;11 (1):6072. doi: 10.1038/s41598-021-84919-x. PubMed PMID:33727568 PubMed Central PMC7966789.

Kronenberg, G, Gertz, K, Schöner, J, Bertram, L, Liman, T, Steinhagen-Thiessen, E et al.. BDNF serum concentrations in 2053 participants of the Berlin Aging Study II. Neurobiol Aging. 2021;101 :221-223. doi: 10.1016/j.neurobiolaging.2021.01.020. PubMed PMID:33636574 .

Jones, G, Trajanoska, K, Santanasto, AJ, Stringa, N, Kuo, CL, Atkins, JL et al.. Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nat Commun. 2021;12 (1):654. doi: 10.1038/s41467-021-20918-w. PubMed PMID:33510174 PubMed Central PMC7844411.

Tijms, BM, Gobom, J, Reus, L, Jansen, I, Hong, S, Dobricic, V et al.. Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics. Brain. 2020;143 (12):3776-3792. doi: 10.1093/brain/awaa325. PubMed PMID:33439986 PubMed Central PMC7805814.

Pešić, M, Dragašević Mišković, N, Marjanović, A, Dobričić, V, Maksimović, N, Svetel, M et al.. Premutations in the FMR1 gene in Serbian patients with undetermined tremor, ataxia and parkinsonism. Neurol Res. 2021;43 (4):321-326. doi: 10.1080/01616412.2020.1863697. PubMed PMID:33403926 .

Hong, S, Prokopenko, D, Dobricic, V, Kilpert, F, Bos, I, Vos, SJB et al.. Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset. Transl Psychiatry. 2020;10 (1):403. doi: 10.1038/s41398-020-01074-z. PubMed PMID:33223526 PubMed Central PMC7680793.

Visser, PJ, Reus, LM, Gobom, J, Jansen, I, Dicks, E, Tsolaki, M et al.. Cerebrospinal fluid total tau levels indicate aberrant neuronal plasticity in Alzheimer's disease. medRxiv. 2020; :. doi: 10.1101/2020.10.29.20211920. PubMed PMID:33173883 PubMed Central PMC7654872.

Walhovd, KB, Fjell, AM, Sørensen, Ø, Mowinckel, AM, Reinbold, CS, Idland, AV et al.. Genetic risk for Alzheimer disease predicts hippocampal volume through the human lifespan. Neurol Genet. 2020;6 (5):e506. doi: 10.1212/NXG.0000000000000506. PubMed PMID:33134508 PubMed Central PMC7577559.

Gisatulin, M, Dobricic, V, Zühlke, C, Hellenbroich, Y, Tadic, V, Münchau, A et al.. Clinical spectrum of the pentanucleotide repeat expansion in the RFC1 gene in ataxia syndromes. Neurology. 2020;95 (21):e2912-e2923. doi: 10.1212/WNL.0000000000010744. PubMed PMID:32873692 .

Shi, L, Winchester, LM, Liu, BY, Killick, R, Ribe, EM, Westwood, S et al.. Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology. J Alzheimers Dis. 2020;77 (3):1353-1368. doi: 10.3233/JAD-200208. PubMed PMID:32831200 PubMed Central PMC7683080.

Kusters, CDJ, Paul, KC, Duarte Folle, A, Keener, AM, Bronstein, JM, Dobricic, V et al.. Genetic risk scores and hallucinations in patients with Parkinson disease. Neurol Genet. 2020;6 (5):e492. doi: 10.1212/NXG.0000000000000492. PubMed PMID:32802953 PubMed Central PMC7413629.

Rieck, L, Bardey, F, Grenkowitz, T, Bertram, L, Helmuth, J, Mischung, C et al.. Mutation spectrum and polygenic score in German patients with familial hypercholesterolemia. Clin Genet. 2020;98 (5):457-467. doi: 10.1111/cge.13826. PubMed PMID:32770674 .

Bertram, L, Tanzi, RE. Genomic mechanisms in Alzheimer's disease. Brain Pathol. 2020;30 (5):966-977. doi: 10.1111/bpa.12882. PubMed PMID:32657454 PubMed Central PMC8018017.

Röhr, F, Bucholtz, N, Toepfer, S, Norman, K, Spira, D, Steinhagen-Thiessen, E et al.. Relationship between Lipoprotein (a) and cognitive function - Results from the Berlin Aging Study II. Sci Rep. 2020;10 (1):10636. doi: 10.1038/s41598-020-66783-3. PubMed PMID:32606300 PubMed Central PMC7326928.

Konijnenberg, E, Tijms, BM, Gobom, J, Dobricic, V, Bos, I, Vos, S et al.. APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease. Alzheimers Res Ther. 2020;12 (1):65. doi: 10.1186/s13195-020-00628-z. PubMed PMID:32460813 PubMed Central PMC7254647.

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