Seven new risk loci for multiple sclerosis found

16. October 2015

In a large, international collaborative effort, LIGA researchers Lill and Bertram established seven novel genetic loci as genuine Multiple Sclerosis (MS) risk loci (i.e. LOC100506457, CD28, LPP, ETS1, DLEU1, LPIN3, and IFNGR2). To this end, they undertook an association study on >21,000 MS patients and healthy controls from Europe and Russia in which they evaluated 11 loci for their role in MS susceptibility. The majority of these loci are shared across autoimmune diseases. This study was published in the  Journal of Medical Genetics..